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$1591528 Locust Street, Wellston, 63103, Missouri, United States
745 reviews
1/28
Spa/Wellness packages
Restaurant
Indoor swimming pool
Business center
Free wifi
Room service
Fitness center
Streaming service (like Netflix)
Welcome to the 21c Museum Hotel St. Louis, where contemporary art meets luxurious comfort! Located at 1528 Locust Street in East Saint Louis, this vibrant 4-star hotel is just 2.8mi from the hustle and bustle of the city center. Starting at just $159 per night, you can indulge in a unique experience that transforms your stay into a delightful journey through creativity and culture—all while having a fantastic time with friends or family!
Step into a world of relaxation with our fantastic amenities, including an inviting indoor swimming pool and a rejuvenating spa with wellness packages that'll leave you feeling like royalty. With a fitness center at your convenience, you'll have no excuse not to stay active during your getaway. For food lovers, our on-site restaurant offers delicious bites to fuel your adventures, while the well-stocked bar is the perfect spot to unwind after exploring the local sights. Service is at the heart of what we do—enjoy 24-hour front desk assistance, room service, and even massage options for that extra pampering.
Don't just take our word for it; with 745 enthusiastic reviews, guests rave about their experiences here, celebrating the unique combination of art, comfort, and stellar service. The soundproof rooms ensure a peaceful night’s sleep, while the terrace provides a lovely view of your surroundings. Come and discover why the 21c Museum Hotel St. Louis is not just a place to stay, but a true experience that infuses luxury with creativity!
As you explore the 21c Museum Hotel St. Louis, prepare to be wowed by the exquisite dining experience awaiting you at our on-site restaurant, Idol Wolf. This modern eatery shines with Spanish flavors, infusing every dish with creativity and flair. Whether you're celebrating a special occasion or simply winding down after a day of exploration, your culinary adventure here will be a highlight of your stay. Pair your meal with a perfectly crafted cocktail from our well-stocked bar, where friendly bartenders are eager to bring your favorite concoctions to life.
Once you've had your fill of delicious food and spirited drinks, step into our indoor swimming pool for a refreshing dip! Open year-round, this oasis invites you to float and relax while basking in the serene atmosphere. For those looking to elevate their wellness journey, our spa is ready and waiting. Book a rejuvenating massage or one of our specialized wellness packages for the ultimate in relaxation. Picture yourself unwinding after a busy day of sightseeing, cocooned in pure bliss—can you think of a better way to recharge?
When it's time to settle in for the night, the thoughtfully designed rooms at the 21c Museum Hotel St. Louis promise a restful slumber. With soundproof walls, you can kick back and unwind without the bustle of the city sneaking in. Each room is bathed in modern elegance, making it a comfortable retreat where you can reflect on the day's adventures. And if you're traveling with family or friends, you'll find spacious options like our Deluxe Suites and generous corner rooms, perfect for making memories together. Come dive into the unique fusion of art, comfort, and modern luxuries—your next unforgettable getaway awaits!
Closest airports
Saint Louis Downtown - Parks Airport
4.9miLambert–St. Louis International Airport
11.7miMidAmerica St. Louis Airport
20.1miSpa/Wellness packages
Restaurant
Indoor swimming pool
Business center
Free wifi
Room service
Fitness center
Streaming service (like Netflix)
Steam room
Spa
Air conditioning
Bar
Terrace
Soundproof rooms
24-hour front desk
Non-smoking rooms
Wheelchair accessible
Elevator
Bathtub
Free toiletries
Show 5 photos
Luxury, 2 Queen Size Beds
2 Queen Size Beds
Flat-screen TV
Refrigerator
+
More details
Indulge in the spacious and luxurious Quadruple Luxury Queen Room with Two Queen Beds boasting 420 sqft of comfort. With amenities such as a private bathroom, flat-screen TV, and air conditioning, your stay will be nothing short of serene and enjoyable.
Show 4 photos
Deluxe, Queen Size
2 Queen Size Beds
365 sqft
Private Bathroom
Bathtub
Flat-screen TV
Streaming service (like Netflix)
+
More details
Offering free toiletries and bathrobes, this quadruple room includes a private bathroom with a bath, a shower and a hairdryer. The quadruple room offers air conditioning, a seating area, a wardrobe, a safe deposit box and a flat-screen TV with streaming services. The unit offers 2 beds.
Show 3 photos
Deluxe, Queen Size, Accessible
2 Queen Size Beds
365 sqft
Private Bathroom
Flat-screen TV
Streaming service (like Netflix)
Refrigerator
+
More details
Offering free toiletries and bathrobes, this quadruple room includes a private bathroom with a walk-in shower and a hairdryer. The quadruple room offers air conditioning, a seating area, a wardrobe, a safe deposit box and a flat-screen TV with streaming services. The unit offers 2 beds.
Show 3 photos
Loft, 2 Queen Size Beds
2 Queen Size Beds
430 sqft
Private Bathroom
Bathtub
Flat-screen TV
Streaming service (like Netflix)
+
More details
Welcome to our spacious Loft with Two Queen Beds, perfect for families and groups of up to 4 adults and 3 children. Enjoy a private bathroom, flat-screen TV with streaming services, and comfortable amenities like air conditioning and a wardrobe.
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Suite
1 King Size Bed
1110 sqft
Private Bathroom
Bathtub
Flat-screen TV
Streaming service (like Netflix)
+
More details
Indulge in luxury with our 21c King Suite, offering over 1100 sqft of space ideal for 2 adults and 1 child. Enjoy a smoke-free environment and impressive amenities for a comfortable stay.
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Deluxe, 2 Queen Size Beds, Accessible
2 Queen Size Beds
365 sqft
Private Bathroom
Bathtub
Flat-screen TV
Streaming service (like Netflix)
+
More details
Indulge in spacious comfort in our accessible Deluxe Room with two queen beds, perfect for a family of four. Unwind in 366 sqft of luxurious space, with no smoking allowed and complimentary accommodations for 4 adults and 3 children.
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Deluxe Suite, Accessible
1 King Size Bed
505 sqft
Private Bathroom
Flat-screen TV
Streaming service (like Netflix)
Refrigerator
+
More details
Indulge in the spacious Deluxe King Suite, with a convenient accessible roll-in shower, perfect for 2 adults and 1 child. Enjoy 506 sqft of luxury without compromising on comfort.
Show 2 photos
Deluxe, 2 Queen Size Beds
2 Queen Size Beds
Flat-screen TV
Refrigerator
x4
+
x3
More details
Experience ultimate comfort in our spacious Deluxe Queen Room with Two Queen Beds, boasting a generous 366 sqft. This family-friendly room accommodates up to 4 adults and 3 children, offering a private bathroom, flat-screen TV, air conditioning, and all the necessary amenities for a perfect stay.
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Library Suite
1 King Size Bed
730 sqft
Private Bathroom
Bathtub
Flat-screen TV
Streaming service (like Netflix)
+
More details
Show 4 photos
Deluxe Suite
1 King Size Bed
270 sqft
Private Bathroom
Bathtub
Flat-screen TV
Streaming service (like Netflix)
+
More details
Show 4 photos
Luxury
2 Queen Size Beds
420 sqft
Private Bathroom
Bathtub
Flat-screen TV
Streaming service (like Netflix)
+
More details
Show 3 photos
Deluxe, King Size, Accessible
1 King Size Bed
310 sqft
Private Bathroom
Flat-screen TV
Streaming service (like Netflix)
Refrigerator
+
More details
8.6
745 reviewsCategories of assessments
Cleanliness
Comfort
Location
Facilities
Staff
Value for money
WiFi quality
Featured reviews:
Morgan
8.2
July 2024
The hotel was absolutely beautiful! Staff was amazing all but the black gentlemen behind bar. He wasn’t as friendly as everyone else had been. The room was beautiful
we definitely had to reclean the room. Floor had not been swept, toenails in the floor. When we first arrived we checked the bed and was getting ready to change the sheets (we brought our own) and we noticed the comforter had visible blood and pee/sweat stains. It did take them awhile to bring us a new clean comforter and when they did we was not in the room but they left all the dirty Lien in our room
Parker
8.2
April 2025
Gorgeous and unique property, being able to explore the museum was very cool! Also has a nice Spanish-themed bar and breakfast restaurant on site. Room was spacious, clean and comfortable, also quiet for a downtown area. Gym and indoor pool (including hot tub, sauna and steam room) were amazing! Unfortunately, valet parking is insanely expensive at $45/night, and staff were extremely rude and unhelpful when I inquired about other parking options. Spent a lot of time moving my car and worrying about meters. Also, contradictory to my booking terms, breakfast was NOT included, so that false advertising was highly disappointing since I believe I paid extra for that.
Family
8.2
March 2025
We loved the breakfast Cafe, and the personality and welcoming attitudes of the staff. We loved the art and being able to search for the bee hives. We loved the game room (pool table and shuffleboard) and that we were close enough to eateries and businesses to walk for something to eat and/or to do. The room was clean and comfortable.
The room was smaller than we thought it would be. We heard noise from plumbing or something every once in a while, and the elevators were an issue. Parking was awful and cost a lot. At one point, we had to go out at 3AM in order to add more time because it wouldn't allow us to add another 24 hours.
Chelsea
9.1
April 2025
The room was beautiful and very comfortable with the lounge seating and table in the corner king room. I really liked the menu offerings at the restaurant conveniently located in the lobby. The art was fun to view and the overall look of the hotel was polished but approachable and just casual enough. The spa facilities looked great as well - steam room and sauna! The proximity to the Gateway Arch was perfect for a stroll from the hotel.
I wish we had been told that a reservation for the dining room would be needed. We were sat in the bar area instead. The spa facilities closed at 6 PM which was much too early for us to be able to enjoy them after returning from our sight seeing walk downtown.
Hannah
8.2
March 2025
Overall really beautiful location with lovely amenities. Didn't have much time to explore but would love to come back and spend time in the gallery.
A few design details that could be improved: 1) Shower door leaked onto the bathroom floor regardless of whether open or closed 2) Furnace fan was loud and would have been an issue if we had needed to turn on heat or air. 3) Hard to find info about room service, had no clue that we should turn the TV on. Appreciate paper being saved, though! 4) Glass window + tile floor in sauna seemed to be weird design choices for comfort. Otherwise the pool area + sauna were SO cool. 5) When I booked, free breakfast was listed as part of the package. However, the café on site did not have a hotel breakfast option. Would remove this from the booking website so as not to mislead guests!
Marci
10
November 2024
Found this hotel for a quick stay to celebrate our 20th anniversary. It was a great choice and a really unique and artsy place. Appreciated the extra effort to make it interesting. The fun wallpaper in the stair well was a good backdrop. We enjoyed visiting the art gallery and there was really nice work in there. An artist we had seen at the Nashville art museum previously had work in here. Fun bonus. The room was modern and clean and we loved the glass shower that gave it an extra wow factor. Didn't get to the pool or the billiards table but we did pickup breakfast from the little cafe on our way out and while the selection was pretty small, it was nice to have a little something before we left. The coffee with honey was really great.
Nothing we came across could have been better
Alison
10
July 2024
Staff were amazing and friendly, bar was fantastic and the restaurant Idol Wolf was superb. We enjoyed using the pool and jacuzzi. Room was really spacious, bathroom enormous, beds super comfortable. Toiletries divine… shower jet was powerful and had options. It was great being able to make a nice coffee or tea. And our girls liked playing table shuffleboard!
We didn’t drive on this trip and sometimes it took a little while to walk downtown or wherever we needed to go (we also took an Uber when we needed to). But we enjoyed the location - peaceful and close enough to lots of places we wanted to go
Karin
9.1
July 2024
The location was wonderful! We were in town for a concert at Busch Stadium. We were able to walk to to and from the concert, so we didn't have to mess around with finding parking near the stadium. The hotel was very clean and comfortable, and the staff was very friendly and helpful! The hotel itself is beautiful. Converted from a YMCA built in 1926, the facilities (especially the pool area and the lobby) and aesthetic are fantastic, especially if you enjoy historical buildings. Bonus win- there is a rubber ducky in the bathroom that you can take with you after your stay! My daughter named ours Louis! We will stay at this hotel again whenever we find ourselves in St. Louis!
The body wash and conditioner were empty in our shower. We had an ice bucket, but we couldn't find an ice machine anywhere in the hotel.
Alexis
9.1
July 2024
The hotel was fabulous! It was so fun to stay here. I loved the decor in the room and throughout the building. The restaurant and bar were wonderful. We LOVED the food. The pool and art gallery were super fun and memorable. Definitely worth it to come here!
The surrounding neighborhood was less inspiring. We came during a hot spell over the summer, so it wasn't pleasant outside. This hotel wasn't ideal for pets, though they were very accommodating, as we were staying with our two dogs as part of our cross-country road trip. However, these are aspects that can be overlooked for an enjoyable stay.
Monica
10
July 2024
The fact that the hotel is a museum is really cool, we enjoyed walking around and seeing all the art. The pool is really nice, it’s a decent sized pool and it wasn’t dirty or anything, there were toys from people the previous night but it didn’t bother me. The hot tub & saunas were really nice too. Location isn’t horrible, we had a concert at enterprise center and it was only a 10 min walk. The bar was really nice too, a little pricey but not bad.
We didn’t have much toilet paper in our room when we arrived but a quick call to the front desk fixed that. I really don’t have any complaints.
Attractions
National Blues Museum
0.7miMissouri Botanical Garden
3.3miAttractions
National Blues Museum
0.7miMissouri Botanical Garden
3.3miAirports
Saint Louis Downtown - Parks Airport
4.9miLambert–St. Louis International Airport
11.7miMidAmerica St. Louis Airport
20.1miIdol Wolf
Cuisines
Ambiances
Location
Availability
Spa/Wellness packages
Restaurant
Indoor swimming pool
Business center
Free wifi
Room service
Fitness center
Streaming service (like Netflix)
Steam room
Spa
Air conditioning
Bar
Terrace
Soundproof rooms
24-hour front desk
Non-smoking rooms
Wheelchair accessible
Elevator
Bathtub
Free toiletries
Accessibility
Toilet with grab rails
Wheelchair accessible
Activities
Game room
Pool table
Temporary art galleries
Bathroom
Bathrobe
Bathtub
Bathtub or shower
Free toiletries
Hairdryer
Private Bathroom
Shower
Toilet
Toilet paper
Towels
Bedroom
Alarm clock
Linens
Wardrobe or closet
Business Facilities
Business center
Meeting/Banquet facilities
Cleaning Services
Daily housekeeping
Dry cleaning
Laundry
Common Areas
Shared lounge/TV area
Entertainment & Family Services
Board games/Puzzles
Food & Drink
Bar
Coffee house on site
Restaurant
Special diet meals (on request)
Vending machine (drinks)
Vending machine (snacks)
Wine/Champagne
Food & drink safety
Breakfast to-go containers
Delivered food covered securely
Food can be delivered to guest accommodation
Front Desk Services
24-hour front desk
ATM on site
Baggage storage
Concierge
Invoice provided
Private check-in/out
General
Air conditioning
Elevator
Facilities for disabled guests
Heating
Hypoallergenic room available
Non-smoking rooms
Pet Friendly
Room service
Smoke-free property
Soundproof rooms
Internet
Free wifi
Kitchen
Refrigerator
Living Area
Desk
Fireplace
Sitting area
Media & Technology
Cable channels
Flat-screen TV
Streaming service (like Netflix)
Outdoors
Outdoor furniture
Terrace
Physical distancing
Cashless payment available
Room Amenities
Iron
Socket near the bed
Safety & security
24-hour security
CCTV in common areas
CCTV outside property
Fire extinguishers
Key card access
Safe
Smoke alarms
Safety features
First aid kits available
Spa
Fitness
Fitness center
Fitness classes
Indoor swimming pool
Locker rooms
Massage
Spa
Spa facilities
Spa lounge/Relaxation area
Spa/Wellness packages
Steam room
Yoga classes
From 16:00
Guests are required to show a photo identification and credit card upon check-in
Until 11:00
Pets are allowed. Charges may apply.
WiFi is available in all areas and is free of charge.
Age restriction may apply
Parking may not be available
Reservations
Call us for our best daily rates
+1 (888) 385-8465Child policies
Children of all ages are welcome.
Children 18 and above will be charged as adults at this property.
To see correct prices and occupancy info, add the number and ages of children in your group to your search.
Crib and extra bed policies
No capacity for extra beds or cribs.
Cash
American Express,
Mastercard,
Visa
This property does not accept cash.
Is it possible to stay with my pet at 21c Museum Hotel St Louis?
Yes, you can stay with your pet at the 21c Museum Hotel St Louis, though charges may apply.
What's the check-in and check-out schedule at 21c Museum Hotel St Louis?
At 21c Museum Hotel St Louis, we have arranged the check-in post 04:00 PM and the room should be vacated by 11:00 AM.
Is there parking available at 21c Museum Hotel St Louis?
Yes, there is parking available at the 21c Museum Hotel St Louis. Public parking is conveniently located nearby, and there is no need to make a reservation. However, please note that parking charges may apply.
What's the nightly rate at 21c Museum Hotel St Louis?
Room rates at 21c Museum Hotel St Louis initiate from $159. Yet, variations occur based on your room and date preferences. For exact rates, please insert your travel dates.
Which room categories can I book at 21c Museum Hotel St Louis?
The hotel offers Deluxe King Rooms and Corner King Rooms, both accommodating 2 adults and 1 child. The Deluxe King Rooms are 312 sqft in size and have 1 King size bed, while the Corner King Rooms are slightly larger at 323 sqft. Both room types do not allow smoking. Additionally, there is a Deluxe Queen Room with Two Queen Beds, which accommodates 4 adults and 3 children. This room is 366 sqft in size and has 2 Queen size beds.
What activities does 21c Museum Hotel St Louis offer?
Guests at 21c Museum Hotel St Louis can indulge in a variety of leisure amenities during their stay. The hotel offers a spa and wellness packages, allowing guests to relax and rejuvenate. There is an indoor swimming pool, perfect for a refreshing swim. Additional facilities include a steam room, spa, hot tub/jacuzzi, and sauna. The fitness center is equipped for those looking to stay active during their stay, with fitness classes and yoga classes available. For those who enjoy games, the hotel offers a pool table and a selection of board games and puzzles.
Guests looking for dining options can dine at the on-site restaurant, Idol Wolf, which offers modern Spanish cuisine.
In terms of pools, there is an indoor pool available, ensuring that guests can enjoy a swim regardless of the weather.
Does 21c Museum Hotel St Louis have a pool for guests?
The hotel has one pool available. The pool is indoors and is open all year round.
Does 21c Museum Hotel St Louis feature its own restaurants?
Yes, the hotel has a restaurant on-site called Idol Wolf. It offers modern ambiances and serves Spanish cuisine.
Does 21c Museum Hotel St Louis accept credit cards?
21c Museum Hotel St Louis does not accept cash but they do accept credit cards such as Visa, American Express, and Mastercard.
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